Juventus dropped their first Europa League points in a 2-2 draw with Rennes, while Benfica thrashed Omonia, Leverkusen beat OFI, and Bournemouth maintained their perfect campaign.
Teenager Alphadjo Cisse became the youngest Italian to score a hat-trick in European club competition, leading AC Milan to a resounding 4-0 victory over RB Salzburg in the Europa League, marking Milan's first continental treble in 24 years.
Aston Villa secured their place in the Europa League final with a dominant 4-0 victory over Nottingham Forest, setting up a clash with Freiburg in Istanbul.
Aston Villa defeated Freiburg 3-0 in the Europa League final, securing their first major trophy since 1996, with goals from Youri Tielemans, Emiliano Buendia and Morgan Rogers.
Nottingham Forest and Aston Villa reach the Europa League semi-finals, while Braga and Freiburg also advance in a dramatic night of European action.
Aston Villa secured a 1-0 victory against Lille in the Europa League, while other matches saw Bologna draw with AS Roma and Porto win against VfB Stuttgart.
Bologna advanced to the Europa League quarter-finals after a thrilling 4-3 win against AS Roma.
Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
Lyon sealed top spot in the Europa League standings while Roma survived a red-card scare to reach the last 16 on a chaotic final league-phase night.
Chris Wood's penalty gives Nottingham Forest a 1-0 edge over Aston Villa in their Europa League semi-final first leg, extending their unbeaten run to nine matches.
Aston Villa secured a 2-1 victory at Basel on Thursday, with goals from Evann Guessand and Youri Tielemans keeping their Europa League campaign on a strong footing.
Nottingham Forest handed manager Sean Dyche the perfect debut with a 2-0 home win over Porto in the Europa League on Thursday, with both goals coming from the penalty spot.
Images from the Europa League semi-finals second leg between Manchester United and Athletic Bilbao, Tottenham Hotspur and Bodo/Glimt, on Thursday.
AS Roma took a big step towards qualifying for the Europa League last 16 with a 2-0 win over VfB Stuttgart on Thursday.
Nine Real Sociedad fans injured in clashes with Lazio ultras
Ange Postecoglou ultimately paid the price for an horrendous English Premier League season which saw Tottenham finish 17th.
Lyon thump Maccabi Tel Aviv to go top, Forest keep on winning
In Lille, substitute Olivier Giroud turned the game on its head in the 80th minute.
The other semi-final will see an Italian side, Milan or Roma, come up against Bayer Leverkusen or West Ham.
Brennan Johnson's bundled first-half goal helped Tottenham Hotspur win a scrappy Europa League final 1-0 against Manchester United on Wednesday.
Liverpool will take on LASK, Union Saint-Gilloise and Toulouse in the Europa League group stage while debutants Brighton & Hove Albion will face Ajax Amsterdam and Olympique de Marseille following the draw on Friday.
Celtic suffered a devastating exit from the Champions League after squandering a four-goal aggregate lead against Austrian side LASK, losing 5-4 overall.
Sevilla maintained their incredible record in the competition after an otherwise difficult season.
Summary of the Europa League semi-final matches played on Thursday.
Rennes denied late Europa League equaliser due to little-known rule
Europe's top club coaches gave their support on Thursday to the much-maligned Europa League.
The win leaves United in 15th place in the Europa League standings on six points from four games.
Atalanta beat Bayer Leverkusen 3-0 in the Europa League final
Jose Mourinho's side top Group G with a maximum nine points, three clear of second-placed Slavia.
The first legs of the ties will take place on February 16, with the return match a week later on February 23.
Mumbai City FC has announced the signing of Serbian defender Lazar Cirkovic on a one-year deal for the 2026-27 Indian Super League season. The experienced 34-year-old has previously played for other ISL clubs and brings a wealth of international experience from European leagues.
However, there was a softening in tone over eventual cases where league seasons may be cancelled -- an outcome UEFA had been quick to oppose.
Arsenal sailed through the Europa League group stages, winning five of their six group matches and take on Sporting next, who overcame Denmark's FC Midtjylland in their playoff.
Action from Europa League matches played on Thursday.
Olympique de Marseille and Lille, two prominent French football clubs, reported that their official stores were looted during the widespread weekend unrest across France, which saw thousands arrested and significant property damage.
In an early match, Norwegian side Bodo/Glimt secured a 3-2 home victory against FC Porto thanks to a brace from Jens Petter Hauge, despite going down to 10 men in the 51st minute.
Arsenal can sustain a Europa League challenge but a top-four finish in the Premier League would be the best way to reach next season's Champions League, manager Arsene Wenger has said.
Forward Rasmus Hojlund scored twice to allow Manchester United to come back from a goal down and get a 2-1 win at six-times Czech champions Viktoria Plzen in the Europa League on Thursday.
UEFA bowed to the inevitable on Wednesday and suspended all Champions League and Europa League matches 'until further notice' due to the coronavirus pandemic.
The teams finished level at 3-3 on aggregate in the tie but the Lisbon club advanced to the quarter-finals after Adan kept out Martinelli's weak effort.
